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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25904f074c01de37b29add0bb2391a3c70afd0ed3fa89bec9b523f4b073c4681' 
  AND token = 'HeEt8nQo3MVqBOXwyMcsbNM/mKwMzxgBCtV9mCkFKlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}