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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0788da7299b936214ba19358e7363c6f077e046732a4444e28277d255ed32744' 
  AND token = 'pOUHLeDyjIDX3ny1nOqp6yMIIMV1LbmzcFcmHsYIA3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}