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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a88fb22e30b57039a26a4ce17504717535da03bb669587bfe526347e60d86c5' 
  AND token = 'ZuR2FvefeVrgB9ZEtGtKICjNkSNA0n0IjUXF9u17nZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}