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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a2321cd964aaffb207a0e1a12043aca539a618c480952a5b10c94b41c21b9ca' 
  AND token = '2l+rbDYqmHYbQXUzkfI3E5twSW/aK8uZ9KgVv90b0HM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}