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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37aa76b5c4a3f4af2ee661745516c65d1224449c51ab8d51ba5a0ba2d60e38b9' 
  AND token = '1WBRzbT5Jpmkhbtvfrc/MB9KIXIM2Zl0slVFI5xrweM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}