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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a995e3b7c6ea332c0fce0b1e9d2820e3da956d07cedc929357a3553c27b5278' 
  AND token = 'eUOC8ML9hH/799Zoh0J7Z0PlaO35zTI2gtnc+iH+HYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}