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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3550327aae59e80691ae2238c473b612c19c782bcc3bdc4321ff6ed6f46b0d6' 
  AND token = '0sReysQG/N+fcl1iftuJFgQj5faSjrk7zZf+28igzH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}