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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0473678706a7e06e3277e28a7e1e4d5ea3663030de07bd031e6f7dcf20a37e3f' 
  AND token = 'N8YLTtcr27MNX/FhRHQhYmpeO4GLz4iXco4nroayCO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}