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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '141d8bbbd2cb4988fba8a6434ed9b642864493ead4a83f6170337f9ce3629dee' 
  AND token = 'cr6bWruw1Zf0j/B56w37b/wfWTGP+FT3rDFyJ8VhvU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}