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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc49e7c07adfc0c80cd60fbf0c4827d85b23f6b5b026858de5377cd87769f790' 
  AND token = 'yxZaOosGjvXxGxAocvTI2Dyb66Z24+BOLB/vV6GkzAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}