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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59d08358a1f8def4ac1e7d0656b70820dffed9269ccd503bc788ac722295bcb6' 
  AND token = 'AWuIcp62KQYU9fcK9Wd/kDMaen9mCwfUABMKzd4W8PY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}