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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e421c3ef2972c90fb3b20ce55b5e25a9f8d5c600c7e3b85e544c77a6dc916ab2' 
  AND token = 'FCd3zqSBWUr+eDtyd9u1A/PiRcMDcZtwwlgBuUf5z24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}