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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f33274ccb3864ab8cdb43930bbbc98e992bd8ecbd8484024fecf46c3bd5a2c3d' 
  AND token = 'UiYnQUG1rE4iJPBYANd7In8ZghFKqTwEG83PgCi4Ovc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}