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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '551c659a878208080e52d5aefb0a0839e68a45abe9662ddc22e1345b03066122' 
  AND token = 'CmWXSrFmp2wZz9S0lL3tjcIUdpBmMPxHy1577madX/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}