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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '415bd2787607d874d1a65176b6d7071e58643e4cd156ca01da2bfff0f8744609' 
  AND token = '1FCL+hS9T8MZGXl5BlGxTbDwGCpE1vYv10ewnYfhx5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}