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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac76f09e0dd95badda0be64be29501c6fa8f1470f0f8de4df521ff6f5945eabb' 
  AND token = 'zsMEMIGgVFR0tCKtFUs79YBco1/RH1JRqJ8/+9KKERo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}