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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '404eceaf2fc373f0eda14a4e1261f28be147916335445ec225b8204c15a76c43' 
  AND token = 'yIX4ORohjo4/OUI5t2ZZ/baXr4yU+U7bTe8/c2tRgV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}