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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fdc123bfc702a77086f83f5acd33379d440f172b86ab5637bb742a56e69cf85' 
  AND token = 'ghAzffxOs6RJdC2xrwDHgxVJHmtAtkqmHO6nDyVTGkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}