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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a39f0e98579d64b4f2e482021d8225e6905531c519a50a2aebb794331337a83' 
  AND token = 'v2b9PSztA5saY7+ZJsI8Sw9Exq/8rhl2NAoLFf8x9o8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}