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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e90c3f1050fd238b7c109ffce3f70a82031fa82d01613cc58d52803b8e9a11a5' 
  AND token = 'ZKCjB0KbDREAbufPuOWLR4/f9KjQL3oVTQhfHe7q2Ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}