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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff8f883ba2a83d386a132376228df9f355d63ad8dfcd70eca401edcf04709f36' 
  AND token = 'mqTvr/ZIg9q3DCP/fWUe0CUnCTV3S0ed1sQtAfTGmCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}