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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e325d7647e90b7a454c233c65276d4ce60168a502412dc5a3814bdef75f0f49' 
  AND token = 'dn/7ZR9O5ZMidPUycSEjuAB3ad6M4eDOG/gxVoNoycc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}