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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '026c4a158012ab131e89a6b7bf78b4cf9ff09d5c9f6ef78bddd2e0100223d79c' 
  AND token = 'uuU24Az8xcwKfLxeKZZalffbim3w28563L1jkIMqgMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}