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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52135c2b84a2e41625a1c4adbcfd7dc8ae2ce27bfcdfb960dc2f522c27569f9c' 
  AND token = '2SEu7HBnEhdCFg8uAI0IF2/1PGek03aIuwqI6fYJtIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}