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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e7d541efd6494c940d289d990b1bd4500b0efa738ccfd03100759de1762c642' 
  AND token = 'L7bdwbMSDgdstlOlyf+0+u9+EAXQcJg2169jdSlBeY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}