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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75889bb2a8459a5385583b93bfa05dc69bbe47b6105d640fbdf58450a0f538d3' 
  AND token = 'lWANromPVEOfNtOHfXVZj8DdZTefMk3itzOLLK2G9aA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}