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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '857aace30195199d0c1a74607108f116d9b94938881c69d3cc25f176294cd887' 
  AND token = 'ZCw4fizYBoWIK0COqb1jekJl0JvaIPWWrY9qgNEAgck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}