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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '424ff44f3c1ac9f38a2996b752060606dbb1aa5db79ca9aa3945fb399a6a9318' 
  AND token = 'QFhECwHvGQx4G85NR+it4L5mTCOt+47EOWtiq0Gxl/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}