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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80dfba6cdb88324f7e81c56ca20406312af1e6ccc3f3246b92d91256b8eb3fa6' 
  AND token = 'emo84aabfpWmU5ASwk49C0ZrN+M1UozTWSjBrWmXYWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}