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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ff9daea3729d93e6ff1802c6be122a68f20b7acfdb5ca591cc4012ac9328fea' 
  AND token = '4P9cDvke5IF0CN+9f3ycxNYDmB7MkMlLBoKq8zhzTbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}