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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea8ff00eff4cf9849f421fc32fc31f02407178758a7d43ca443d01c5a80ef4ac' 
  AND token = 'X20bOKEtC4aAjgTkMEy/a4wWSiuf7boZO4boMEp7KG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}