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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e1e6a91110051af3b34f89a4642aa5c5c9e49b447d1a81abe5b8037e37b7296' 
  AND token = 'DJJKzzutw/t1DRC8bt0a7zuU/WUX0U601ATuqjReOuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}