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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f9204a46c36a9e3ea81170db2feb61baa7c49f22e1d65749a1821f028671e6e' 
  AND token = 'cCTWGIf2/sUcHgTBPMlzuehvJHPvPzNHoeBnAd9ZtZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}