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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b5c337ffa1e3bd3f63eef44765efc27b433123d95cc057027b94c47ec92e543' 
  AND token = 'G9oVtKU2dw1FiQXY9+bZgriRmnXrSaIiWk8bWhAzH54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}