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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7650f11216660dd87446e784c58e6d7577834e8980a9211148f4049df804515' 
  AND token = 'Rn7TTVx/qikPx+7xnZiaiOHhXxNrjF3b6Q/aTNp8Vj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}