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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c7d661b2e4b9be71fb428954c20539f727416f140a759c0046a10ac2ac67fb0' 
  AND token = 'MiwGE9DgKgY+dNO3vFe8Cp+55OMsfCRnkw3dz9/oZEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}