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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38b7c56104c1a1121fbc1ec9f07450ab296a2318c7a37fd5d884a1f56df17c90' 
  AND token = 'TYTS8lWYEoUXsXk+cH6L01Ct5niLl8FrII8dYaA+ewQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}