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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd2a5df6e5c7336f766930aa02749b0625f11fb64f504adc4211dfb07ae3fa75' 
  AND token = 'NRbPSdBl6i4etpMUkubZuo65v20D3WE+229HoPTAT40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}