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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec17cfe4347911471bf656c5663698307cff7d152e5046d5397eee5ed4872482' 
  AND token = 'riE0aXZU5A8j+8MP7NLJ6/6fRrheqrmg32TQQ6DPK+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}