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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43ea142b0ec52614126c517b00d1d2cae57c7d2b87019a8cbc3942d04dba027b' 
  AND token = '2T8zmdfQkVSsrWfuyxsybZr0eJyEm/HNP+Qt4Ry40Ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}