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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f7990e7abdb59a683e6bac7b5637dd5640d82dc5186f806a17bc4bedeffc6b9' 
  AND token = 'JF3Fddi3oWt5qfyA85W8TL8+XTKghKpDyHsf74Ao880=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}