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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8eb202bf80f20607af1158e7a92d4b8440bfd112587d768925553733690b6a3b' 
  AND token = 'dikdo0t+TwExlj4kUFH7z1qbvmyMfrTGM7+Yn7q2ilE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}