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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6541e545799ec5477c29472799ed95079ab21bed3c30020b6c6ff2908563693' 
  AND token = '6Q1jXYMtJPS9NcJS4fABPvVo62LYsPcj38X03LCR5RI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}