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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a2cd1d95ea05689771cdf9fc6cceb6f02c7a63f12ff5e2c7f12e9db041157b2' 
  AND token = 'Qj9dAaaBWwGrOLqBw+hliUzAXe6305n0/hCxlba9ELM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}