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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d1f33ff5a2f8966acb46307b7b0dfb6c63da922ead134bd729904c416f97b17' 
  AND token = 'CnLRcgVSQGZUGFEEuro0Yp7YkgWsgsLD7S9bK8p7RGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}