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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3080420dcdbc95542b8f51f044fe72e098bc3fa8c0b2fa4cd530744c3f17357c' 
  AND token = 'z4rX1QqNPcH3FsFvRs5sfJ6Ei1WyiLSQEXHqIc83A5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}