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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9f1fef745079809ae0bcece9a3ea720f494d9d708a1df7cbe935966901c1658' 
  AND token = 'CtRcPDcS2SPag5E8Gi9dvyULaqrGtKRIO0mD6YUUIn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}