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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24b5f30af529369ebec9cda90199d4b7856e8f9eff5f554b5ffc23b75e8e83aa' 
  AND token = 'tClPFd6S1OGuCOqcxS92by+Vp/j0Jdy1RLCnEBtWq2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}