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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9775970a77cd11c8d36e364df5b45118b8e68da73a0c9055300ddd3f6659f9de' 
  AND token = 'jrYILU5ufxNNl5zQkOORV8nKM+ExtVPy0f4GiFsuCCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}