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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b499e9fcdd2ff12f984d02629c8acba85cd5a27df934a835ac0498bf1e855849' 
  AND token = 'iB8L0tE4RxnMmhb20XPyN0klgptftgqvhE4+KTpvlcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}